NU7441

Overview
Catalog #	bs-83029c-5-mg
Product Name	NU7441
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	NU7441 is a potent (IC50 = 13 nM) and selective ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK).1,2 It increased the toxicity of ionizing radiation and etoposide on SW620 human colon cancer lines via impeding of DNA double-strand break repair.3 NU7441 also increased the radio/chemosensitivity of various other cancer cell lines.3-6
Description	CAS Number: 503468-95-9 Chemical Name: 8-Dibenzothiophen-4-yl-2-morpholin-4-ylchromen-4-one Molecular weight: 413.49 Formula: C25H19NO3S Solubility: DMSO (10 mg/ml) Physical Properties: Off-white to beige solid Purity: 98% by TLC NMR (Conforms)