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Binimetinib

Overview
Catalog # bs-83020c-5-mg
Product Name Binimetinib
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information Binimetinib (606143-89-9) is a potent (IC50 = 12 nM) and selective allosteric inhibitor of MEK1/2.1,2 Recently approved by the FDA for treatment of melanoma in combination with Encorafenib. Binimetinib has had limited success as monotherapy but has shown promise in combination with other chemotherapeutic agents.3-5
Description CAS Number: 606143-89-9

Chemical Name: 6-(4-Bromo-2-fluoroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide

Molecular weight: 441.23

Formula: C17H15BrF2N4O3

Solubility: DMSO (25 mg/ml)

Physical Properties: White solid

Purity: 99% by HPLC NMR (Conforms)