Fruquintinib
| Overview | |
| Catalog # | bs-83018c-5-mg |
| Product Name | Fruquintinib |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Fruquintinib is a potent and highly selective inhibitor of VEGFR kinase (IC50’s: VEGFR1= 33 nM, VEGFR2 = 35 nM, VEGFR3 = 0.5 nM).1 It potently inhibited VEGF/VEGFR signaling and cell proliferation in HUVECs and HLECs and prevented angiogenesis in vitro. Fruquintinib is currently is several clinical trials against metastatic colorectal cancer2 and nonsquamous non-small-cell lung cancer3. |
| Description | CAS Number: 1194506-26-7 Chemical Name: 6-(6,7-Dimethoxyquinazolin-4-yl)oxy-N,2-dimethyl-1-benzofuran-3-carboxamide Molecular weight: 393.40 Formula: C21H19N3O4 Solubility: DMSO (5 mg/ml) Physical Properties: White soliod Purity: 98% by HPLC NMR (Conforms) |
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