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KC7F2

Overview
Catalog # bs-82999c-10-mg
Product Name KC7F2
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information KC7F2 is an inhibitor of HIF-1α (IC50 = 20 µM).1 It inhibited HIF-mediated transcription in cells derived from glioma, breast, and prostate cancers. The mechanism of action of KC7F2 is via down-regulation of HIF-1α protein synthesis accompanied by suppression of phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 and p70 S6 kinase, key regulators of HIF-1α protein synthesis.
Description CAS Number: 927822-86-4

Chemical Name: N,N'-(Dithiodi-2,1-ethanediyl)bis[2,5-dichlorobenzenesulfonamide

Molecular weight: 570.38

Formula: C16H16Cl4N2O4S4

Solubility: DMSO (>25 mg/ml)

Physical Properties: Off-white solid

Purity: 98% by HPLC, NMR (Conforms)