UNC1999
| Overview | |
| Catalog # | bs-82908c-5-mg |
| Product Name | UNC1999 |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | UNC1999 is an orally bioavailable, highly selective inhibitor of both wild-type and mutant EZH1 and EZH2 lysine methyltransferases (IC50’s = 45 nM and 2 nM respectively).1 Inhibition of EZH2 with UNC1999 enhanced the efficacy of gefitinib in suppressing the proliferation of colon cancer cells |
| Description | CAS Number: 1431612-23-5 Chemical Name: N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-1-propan-2-yl-6-[6-(4-propan-2-ylpiperazin-1-yl)pyridin-3-yl]indazole-4-carboxamide Molecular weight: 569.74 Formula: C33H43N7O2 Solubility: DMSO (10 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms) |
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