GW1100

Overview
Catalog #	bs-82889c-5-mg
Product Name	GW1100
Specifications
Storage Buffer	Beige solid
Storage Condition	-20°C
Target
Product Information	Selective antagonist of GPR40. GW1100 inhibits GRP40-mediated Ca2+ increases stimulated GW9508 or linoleic acid (pIC50 = 5.99 for either agonist).1 The effects of GPR40 activation on insulin secretion in cells are also blocked by the addition of GW1100. GW1100 does not influence calcium mobilization mediated by GPR120.
Description	CAS Number: 305974-70-9 Chemical Name: 1-(4-Ethoxycarbonylphenyl-2-(4-fluorobenzylthio)-5-(2-ethoxy-5-pyrimidinylmethyl)-4-pyrimidinone Molecular weight: 520.59 Formula: C27H25FN4O4S Solubility: DMF (5 mg/ml) DMSO (2 mg/ml Physical Properties: White solid Purity: 96% by LCMS NMR (Conforms)