Afatinib

Overview
Catalog #	bs-82885c-10-mg
Product Name	Afatinib
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Afatinib is a clinically useful kinase inhibitor approved for the treatment of non-small cell lung cancer. It is a potent and highly selective inhibitor of mutant and wild-type EGFR (IC50 = 0.5 nM) and HER2 (IC50 = 14 nM).
Description	CAS Number: 850140-72-6 Chemical Name: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2E-butenamide Molecular weight: 485.94 Formula: C24H25ClFN5O3 Solubility: DMSO (>25 mg/ml) Ethanol (25 mg/ml) Physical Properties: Pale yellow solid Purity: 99% by HPLC, NMR (Conforms)