Sulfopin

Overview
Catalog #	bs-82869c-5-mg
Product Name	Sulfopin
Specifications
Storage Buffer	Pale yellow solid
Storage Condition	-20°C
Target
Product Information	Potent and selective covalent inhibitor of peptidyl-prolyl isomerase NIMA interacting-1 (Pin1) (Ki = 17 nM).1 Although it displayed little to no cytotoxicity against a panel of 300 cancer cell lines, it had a significant impact on cancer cell growth after prolonged treatment. It suppressed MYCN-driven neuroblastoma initiation and the growth and survival of primary neuroblastoma tumor cell transplants in zebrafish.
Description	CAS Number: 2451481-08-4 Chemical Name: 2-Chloro-N-(2,2-dimethylpropyl)-N-(1,1-dioxothiolan-3-yl)acetamide Molecular weight: 281.8 Formula: C11H20ClNO3S Solubility: DMSO (25 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms)