Epalrestat

Overview
Catalog #	bs-82863c-5-mg
Product Name	Epalrestat
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Epalrestat is an aldose reductase inhibitor (IC50 = 10 nM (rat lens) and 25 nM (human placenta).1,2 It reduces sorbitol accumulation in the sciatic nerve, erythrocytes and ocular tissue. May be used to prevent or slow the progression of diabetic neuropathy.3
Description	CAS Number: 82159-09-9 Chemical Name: 2-[(5Z)-5-[(E)-3-phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic acid Molecular weight: 319.40 Formula: C15H13NO3S2 Solubility: DMSO (5 mg/ml) Physical Properties: Yellow solid Purity: >98% (TLC: 5% Methanol/methylene chloride + 0.5% HOAc; Rf = 0.21)