LDC1267

Overview
Catalog #	bs-82862c-5-mg
Product Name	LDC1267
Specifications
Storage Buffer	White to off-white glassy solid
Storage Condition	-20°C
Target
Product Information	LDC1267 is a potent and selective inhibitor of the TAM kinases Tyro3, Axl, and Mer (IC50s respectively: 8 nM, <5 nM, 29 nM).1 It was able to activate the innate immune system and enhance NK killer cell activity to kill cancer metastases in vivo.
Description	CAS Number: 1361030-48-9 Chemical Name: N-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluoro-2-methylphenyl)-1H-pyrazole-3-carboxamide Molecular weight: 560.56 Formula: C30H26F2N4O5 Solubility: DMSO (25 mg/ml) Physical Properties: Off-white solid Purity: >98% by HPLC NMR (Conforms)