SLF1081851

Overview
Catalog #	bs-82854c-5-mg
Product Name	SLF1081851
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	SLF1081851 is a sphingosine-1-phosphate transporter (Spns2) inhibitor. It inhibited sphingosine-1-phosphate (S1P) release in HeLa cells: IC50 = 1.93 µM. SLF1081851 is active in vivo and decreased lymphocyte counts and plasma S1P levels in mice and rats. Spns2 inhibitors represent potential alternative immunomodulatory agents to S1P receptor agonists as they are able in induce lymphopenia without drastic changes to systemic S1P levels or stimulating the S1P1-5 signaling pathway.
Description	CAS Number: 2763730-97-6 (free base) Chemical Name: 3-(3-(4-Decylphenyl)-1,2,4-oxadiazol-5-yl)propan-1-amine hydrochloride Molecular weight: 379.79 Formula: C21H33N3O·HCl Solubility: DMSO (30 mg/ml) Ethanol (7 mg/ml) Physical Properties: White solid Purity: >98% by HPLC NMR (Conforms)