Emricasan

Overview
Catalog #	bs-82839c-5-mg
Product Name	Emricasan
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Emricasan is a liver-targeted antiapoptotic pan-caspase inhibitor.1,2 It has been investigated as a hepatoprotective agent in the treatment of liver ischemia3 and NASH/NAFLD liver injury4,5. Emricasan protected SNB-19 cells against cell death induced by Zika virus strains MR766, FSS13025, and PRVABC59.6 Emricasan improves the viability of hPSCs and their differentiated progeny when used in a small molecule cocktail (CEPT) containing chroman 1, polyamines and trans-ISRIB.7
Description	CAS Number: 254750-02-2 Chemical Name: (3S)-3-[[(2S)-2-[[2-(2-tert-butylanilino)-2-oxoacetyl]amino]propanoyl]amino]-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic acid Molecular weight: 569.51 Formula: C26H27F4N3O7 Solubility: DMSO (20 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Confirms)