V-9302

Overview
Catalog #	bs-82831c-5-mg
Product Name	V-9302
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Selective inhibitor of the alanine-serine-cysteine transporter 2 (ASCT2 or SLC1A5; IC50 = 9.0 µM rat and 9.6 µM human).1,2 It inhibited the uptake of both glutamine and possibly other amino acids in human cancer cells and reduced in vitro viability by at least 20% in more than half of 29 cancer cell lines screened.2 V-9302 decreased mTOR activity, elevated autophagy, and increased oxidative stress in multiple animal cancer models.2-5
Description	CAS Number: 1855871-76-9 Chemical Name: (2S)-2-Amino-4-[bis[[2-[(3-methylphenyl)methoxy]phenyl]methyl]amino]butanoic acid Molecular weight: 538.69 Formula: C34H38N2O4 Solubility: DMSO (>70 mg/ml) Ethanol (>30 mg/ml) Physical Properties: Off-white solid Purity: 98% by HPLC NMR (Conforms)