NE-100

Overview
Catalog #	bs-82820c-5-mg
Product Name	NE-100
Specifications
Storage Buffer	Pale pink/purple solid
Storage Condition	-20°C
Target
Product Information	NE-100 is potent inhibitor of the sigma receptor () with selectivity for sigma-1 (IC50 = 1.5 nM) over sigma-2 (IC50 = 85 nM).1,2 NE-100 suppressed ischemia-induced neuronal cell death in mice via upregulation of GPR78 through the ATF6 pathway resulting in suppression of ER stress-induced cell death in a sigma 1 independent manner.3
Description	CAS Number: 149409-57-4 Chemical Name: 4-Methoxy-3-(2-phenylethoxy)-N,N,dipropylbenzeneethanamine hydrochloride Molecular weight: 391.97 Formula: C23H33NO2·HCl Solubility: DMSO (>25 mg/ml) Water (10 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms)