PITSTOP2
Overview | |
Catalog # | bs-82818c-5-mg |
Product Name | PITSTOP2 |
Specifications | |
Storage Buffer | White solid |
Storage Condition | -20°C |
Target | |
Product Information | PITSTOP2 inhibits clathrin-mediated endocytosis via blockade of endocytic ligand association with the clathrin terminal domain leading to clathrin coat assembly inhibition.1 It was able to cause a collapse of the nucleocytoplasmic permeability barrier and a reduction of Importin-ß binding.2 PITSTOP2 reduced viability in HeLa cells by trapping dividing cells in metaphase through loss of mitotic spindle integrity.3 |
Description | CAS Number: 1332879-52-3 Chemical Name: N-[(5Z)-5-[(4-Bromophenyl)methylidene]-4-oxo-1,3-thiazolidin-2-ylidene]naphthalene-1-sulfonamide Molecular weight: 473.36 Formula: C20H13BrN2O3S2 Solubility: DMSO (>30 mg/ml) Physical Properties: Pink solid Purity: >98% by TLC NMR (Conforms) |