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H-151

Overview
Catalog # bs-82808c-10-mg
Product Name H-151
Specifications
Storage Buffer Orange solid
Storage Condition -20°C
Target
Product Information H-151 is an inhibitor of the signaling molecule STING in mouse and human cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. It reduced systemic cytokine response in mice treated with the STING agonist 10-carboxymethyl-9-acridanone and showed efficacy in Trex-/- mice.
Description CAS Number: 941987-60-6

Chemical Name: N-(4-Ethylphenyl)-N’-1H-indol-3-yl urea

Molecular weight: 279.34

Formula: C17H17N3O

Solubility: DMSO (25 mg/ml)

Physical Properties: Off-white solid

Purity: 98%, NMR (Conforms)