C-176

Overview
Catalog #	bs-82806c-10-mg
Product Name	C-176
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	C-176 is an inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. Treatment of Trex-/- mice with C-176 resulted in a significant reduction in serum levels of Type I Interferons and amelioration of systemic inflammation.
Description	CAS Number: 314054-00-7 Chemical Name: N-(4-Iodophenyl)-5-nitrofuran-2-carboxamide Molecular weight: 358.09 Formula: C11H7IN2O4 Solubility: DMSO (25 mg/ml) Physical Properties: Brown or yellow solid Purity: 98%