Raltitrexed

Overview
Catalog #	bs-82780c-10-mg
Product Name	Raltitrexed
Specifications
Storage Buffer	Pale yellow solid
Storage Condition	-20°C
Target
Product Information	Raltitrexed is an inhibitor of thymidylate synthase with significantly increased potency in many cancer cell lines when compared with 5-fluorouracil.1,2 It is also an inhibitor of the methyltransferase G9a (IC50 = 120 nM) and decreased Aß aggregates in C. elegans indicating therapeutic potential for the treatment of Alzheimer’s disease.3
Description	CAS Number: 112887-68-0 Chemical Name: (2S)-2-[[5-[Methyl-[(2-methyl-4-oxo-3H-quinazolin-6-yl)methyl]amino]thiophene-2-carbonyl]amino]pentanedioic acid Molecular weight: 458.49 Formula: C21H22N4O6S Solubility: DMSO (>25 mg/ml) Physical Properties: Pale yellow solid Purity: >98% by HPLC NMR (Conforms)