SP2509

Overview
Catalog #	bs-82761c-5-mg
Product Name	SP2509
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Potent (IC50 = 13 nM) and reversible inhibitor of the histone demethylase LSD1 (KDM1A).1 It is inactive against the closely related flavin enzymes MAO A,B as well as lactate dehydrogenase, several CYP’s and hERG. LSD1 regulates the balance between self-renewal and differentiation of stem cells and is highly expressed in various cancers.2-6 SP2509 promotes autophagy in neuroblastoma cells.7
Description	CAS Number: 1423715-09-6 Chemical Name: (E)-N’-(1-(5-Chloro-2-hydroxyphenyl)ethylidene)-3-(morpholinosulfonyl)benzohydrazide Molecular weight: 437.9 Formula: C19H20ClN3O5S Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms)