EN450

Overview
Catalog #	bs-82736c-5-mg
Product Name	EN450
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	EN450 is a molecular glue that covalently interacts with a cysteine residue on the E2 ubiquitin ligase UBE2D. It displayed anti-proliferative effects in HAP1 leukemia cells. EN450s antiproliferative effects were elicited via proteasome-dependent degradation of nuclear factor kappa B subunit 1(NFkB1).1
Description	CAS Number: 793719-01-4 Chemical Name: N-(2-Chloro-5-(N,N-dimethylsulfamoyl)phenyl)acrylamide Molecular weight: 288.75 Formula: C11H13ClN2O3S Solubility: DMSO (>80 mg/ml) Physical Properties: White to off-white solid Purity: >98% by HPLC , NMR (Conforms)