TH301

Overview
Catalog #	bs-82723c-5-mg
Product Name	TH301
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	TH301 is an isoform-selective stabilizer of the circadian clock protein CRY2. It dose-dependently lengthened the circadian period in Bmal1-dLuc and Per2-dLuc reporter cells. TH301 strongly enhanced rosiglitazone-dependent brown adipocyte differentiation revealing the importance of CRY-dependent regulation of energy metabolism and a possible new lead for anti-obesity therapeutics.
Description	CAS Number: 450338-32-6 Chemical Name: 1-(4-Chlorophenyl)-N-[2,6-dihydro-2-(4-methoxyphenyl)-5,5-dioxido-4H-thieno[3,4-c]pyrazol-3-yl]cyclopentanecarboxamide Molecular weight: 485.98 Formula: C24H24ClN3O4S Solubility: DMSO (25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (conforms)