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KL101

Overview
Catalog # bs-82722c-5-mg
Product Name KL101
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information KL101 is an isoform-selective stabilizer of the circadian clock protein CRY1. It dose-dependently lengthened the circadian period in Bmal1-dLuc and Per2-dLuc reporter cells. KL101 strongly enhanced rosiglitazone-dependent brown adipocyte differentiation revealing the importance of CRY-dependent regulation of energy metabolism and a possible new lead for anti-obesity therapeutics.
Description CAS Number: 396721-89-4

Chemical Name: N-(2-(2,4-Dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)-3,4-dimethylbenzamide

Molecular weight: 377.51

Formula: C22H23N3OS

Solubility: DMSO (25 mg/ml)

Physical Properties: White solid

Purity: 98% by HPLC NMR (Conforms)