Elafibranor
Overview | |
Catalog # | bs-82719c-5-mg |
Product Name | Elafibranor |
Specifications | |
Storage Buffer | Orange solid |
Storage Condition | -20°C |
Target | |
Product Information | Elafibranor is a dual PPARalpha/delta agonist (EC50 PPARalpha = 10-20 nM; PPARdelta = 100-150 nM).1 It was able to decrease plasma triglycerides levels1, increase HDL cholesterol levels in human studies1, and improve hepatic and peripheral insulin sensitivity2. Elafibranor’s antidiabetic effects in db/db were without the adverse cardiac effects seen in PPARgamma agonism.3 Elafibranor has also been shown to have therapeutic promise in the treatment of nonalcoholic steatohepatitis (NASH).4-6 |
Description | CAS Number: 923978-27-2 Chemical Name: 2-[2,6-Dimethyl-4-[(E)-3-(4-methylsulfanylphenyl)-3-oxoprop-1-enyl]phenoxy]-2-methylpropanoic acid Molecular weight: 384.49 Formula: C22H24O4S Solubility: DMSO (>25 mg/ml) Physical Properties: Pale yellow solid Purity: 98% by HPLC NMr (Conforms) |