Dyclonine HCl

Overview
Catalog #	bs-82717c-500-mg
Product Name	Dyclonine HCl
Specifications
Storage Buffer	White solid
Storage Condition	RT
Target
Product Information	Dyclonine is a topical anesthetic which has been used for oral and throat analgesia.1 Enhances neuronal mitochondrial function, potentiating respiration and providing protection against insults associated with neurodegenerative disorders.2 Inhibits aldehyde dehydrogenase ALDH3A1 resulting in accumulation of 4-hydroxynonenal, which renders head and neck squamous cell carcinoma cells sensitive to the cystine-glutamate antiporter inhibitor, sulfasalazine.3 Rescues frataxin deficiency in animal models as well as in buccal cells of patients with Friedreich’s Ataxia.4 Enhances the cytotoxic effect of proteasome inhibitors MG-1325 and bortezomib6 in cancer cells.
Description	CAS Number: 536-43-6 Chemical Name: 4'-Butoxy-3-piperidinopropiophenone, hydrochloride Molecular weight: 325.87 Formula: C18H27NO2 ∙ HCl Solubility: DMSO (20 mg/ml) Water (25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms)