JNJ-63533054

Overview
Catalog #	bs-82716c-5-mg
Product Name	JNJ-63533054
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Potent and selective brain-penetrant GPR139 agonist (EC50=16 nM) an orphan G-protein-coupled receptor expressed in the CNS.1 Tritium-labeled JNJ-63533054 binds to cell membranes expressing GPR139 and can be displaced by putative endogenous ligands.2 Decreases compulsive-like alcohol drinking and hyperalgesia in alcohol-dependent rodents.3 Suppresses morphine intake in a mouse self-administration model.4
Description	CAS Number: 1802326-66-4 Chemical Name: (S)-3-Chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl) benzamide Molecular weight: 316.78 Formula: C17H17ClN2O2 Solubility: DMSO (35 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMr (Conforms)