UPF-1069
Overview | |
Catalog # | bs-82710c-5-mg |
Product Name | UPF-1069 |
Specifications | |
Storage Buffer | Orange solid |
Storage Condition | -20°C |
Target | |
Product Information | A selective PARP-2 inhibitor (IC50=0.3 µM and ~ 27-fold selective against PARP-1).1,2 Increases apoptosis in hippocampal slices but protects cortical cells in models of post-ischemic brain damage.3 Blocks the interaction between PARP-2 and FOXA1, attenuating androgen receptor-mediated gene expression and inhibiting androgen receptor-positive prostate cancer growth.4 |
Description | CAS Number: 1048371-03-4 Chemical Name: 5-(2-Oxo-3-phenylethoxy)-1(2H)-isoquinolinone Molecular weight: 279.29 Formula: C17H13NO3 Solubility: DMSO (40 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC, NMR (Conforms) |