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Urolithin A

Overview
Catalog # bs-82705c-5-mg
Product Name Urolithin A
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information Microbial metabolite of dietary ellagitannins produced in the gut.1 It has been shown to induce mitophagy and prolong lifespan in C. elegans and increase muscle function in rodents.2 It promotes mitophagy and suppresses NLRP3 inflammasome activation in LPS-induced BV2 microglial cells and in an MPTP-induced Parkinson’s disease model.3 The pro-mitophagy activity of UA may be beneficial in Alzheimer’s disease.4 Ex vivo UA-treated T cells display improved anti-tumor function.5
Description CAS Number: 1143-70-0

Chemical Name: 3,8-Dihydroxy-6H-dibenzo[b,d]pyran-6-one; 2′,7-Dihydroxy-3,4-benzocoumarin

Molecular weight: 228.2

Formula: C13H8O4

Solubility: DMSO (50 mg/ml)

Physical Properties: Pale-yellow solid

Purity: >98% by HPLC NMR (Conforms)