R-59022
| Overview | |
| Catalog # | bs-82693c-5-mg |
| Product Name | R-59022 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | R-59022 is a diacylglycerol kinase (DAGK) inhibitor, nonselective for DAGK isotypes (IC50=2.8 µM in intact platelets).1 Induces autophagy and apoptosis in NG108-15 neuronal cells via an mTOR-independent mechanism.2 Prevents conjugated linoleic acid-mediated inflammatory signaling and insulin resistance in human adipocytes.3 Blocks filovirus internalization in host cells.4 |
| Description | CAS Number: 93076-89-2 Chemical Name: 6-[2-[4-[(4-Fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one Molecular weight: 459.58 Formula: C27H26FN3OS Solubility: DMSO (25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms) |
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