Allopregnanolone

Overview
Catalog #	bs-82686c-5-mg
Product Name	Allopregnanolone
Specifications
Storage Buffer	Black solid
Storage Condition	-20°C
Target
Product Information	Endogenous neurosteroid which acts as a positive allosteric modulator of GABAA receptors.1,2 Recently FDA approved (Brexanolone) for postpartum depression.3 Inhibits TLR4 receptor activation and inflammatory signaling in macrophages and brain.4 Inhibits glutamate release5 and displays neuroprotective effects in various animal models6.
Description	CAS Number: 516-54-1 Chemical Name: (3α,5α)-3-Hydroxy-pregnan-20-one Molecular weight: 318.49 Formula: C21H34O2 Solubility: DMSO (32 mg/ml) Ethanol (32 mg/ml) Physical Properties: White or off-white solid Purity: 98% by HPLC NMR (Conforms)