TPPU

Overview
Catalog #	bs-82680c-5-mg
Product Name	TPPU
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	TPPU is a potent and selective inhibitor of both murine and human soluble epoxide hydrolase, IC50=2.8 and 3.7 nM respectively.1 It alleviated blood brain barrier damage and attenuated neuronal injury in a mouse intracerebral hemorrhage model2 and displays neuroprotective effects in ischemic injury3. It reduces neuroinflammation in a mouse model of Alzheimer’s disease.4 It improves insulin resistance and reduced hypertension in mouse models.5 Cell permeable and active in vivo.
Description	CAS Number: 1222780-33-7 Chemical Name: N-[1-(1-Oxopropyl)-4-piperidinyl]-N’-[4-trifluoromethoxy)phenyl]urea Molecular weight: 359.35 Formula: C16H20F3N3O3 Solubility: DMSO (40 mg/ml) Physical Properties: White or off-white solid Purity: >98% by HPLC NMR (Conforms)