CLP-3094
| Overview | |
| Catalog # | bs-82670c-5-mg |
| Product Name | CLP-3094 |
| Specifications | |
| Storage Buffer | Beige solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | GPR142 is highly expressed in the pancreas and immune system and shares 33% homology with GPR1391. Endogenous agonists identified to date include aromatic amino acids such as tryptophan and phenylalanine2. CLP-3094 was identified as a potent and selective GPR142 antagonist with an IC50=2.3 M against 1 mM L-tryptophan. It inhibited insulin secretion from islets induced by L-tryptophan and other agonists and displayed anti-inflammatory activity in a mouse arthritis model.3 |
| Description | CAS Number: 312749-73-8 Chemical Name: 2-{[2-(4-Chlorophenoxy)ethyl]thio}-1H-benzimidazole Molecular weight: 304.79 Formula: C15H13ClN2OS Solubility: DMSO (45 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms) |
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