CK-666

Overview
Catalog #	bs-82667c-5-mg
Product Name	CK-666
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	A potent, selective and reversible inhibitor of ARP2/3 complex (actin related proteins 2 and 3) with an IC50 = 4 µM for human ARP2/3.1 Blocks actin nucleation and radically alters lamellipodial actin architecture, suspended cell shape and the cell spreading process.2 CK-666 attenuates BBB dysfunction induced by methamphetamine3. It is an important new tool for studying actin assembly and the diverse range of actin-related processes in normal4 and pathophysiology5.
Description	CAS Number: 442633-00-3 Chemical Name: 2-Fluoro-N-[2-methyl-1H-indol-3-yl)ethyl]benzamide Molecular weight: 296.34 Formula: C18H17FN2O Solubility: DMSO (45 mg/ml) Ethanol (30 mg/ml) Physical Properties: Cream-colored solid Purity: 98% by TLC, NMR (Conforms)