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2GBI

Overview
Catalog # bs-82646c-50-mg
Product Name 2GBI
Specifications
Storage Buffer white or off-white solid
Storage Condition RT
Target
Product Information A selective and state-dependent blocker of voltage-gated proton channels (Hv1).1 2GBI blocks the channel by binding to the voltage-sensing domain from its intracellular side.2,3 Inhibition of Hv1 is a potentially new target of intervention in various pathophysiological processes including inflammatory, cancer, bone resorption and neurodegenerative disease.4
Description CAS Number: 5418-95-1

Chemical Name: 2-Guanidinobenzimidazole

Molecular weight: 175.19

Formula: C8H9N5

Solubility: DMSO (50 mg/ml) Water (4 mg/ml)

Physical Properties: Beige solid

Purity: 95% by HPLC NMR (Conforms)