CH-223191

Overview
Catalog #	bs-82644c-5-mg
Product Name	CH-223191
Specifications
Storage Buffer	Off-white to pale yellow solid
Storage Condition	-20°C
Target
Product Information	Arylhydrocarbon (AhR) receptor antagonist, IC50=30 nM.1 Blocks endogenous AhR agonist-induced differentiation of Th17 cells.2 Promotes expansion of human hematopoietic stem cells.3 Mitigates cytokine-mediated inflammatory signaling in human fibroblast-like synoviocytes.4 An important tool for probing the involvement of AhR in the toxicity of various environmental toxins such as TCDD and other dioxins.5
Description	CAS Number: 301326-22-7 Chemical Name: 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl]-1H-pyrazole-5-carboxamide Molecular weight: 333.39 Formula: C19H19N5O Solubility: DMSO (25 mg/ml) Ethanol (10 mg/ml) Physical Properties: Orange solid Purity: 98% by TLC, NMR (Conforms)