ALLN

Overview
Catalog #	bs-82633c-5-mg
Product Name	ALLN
Specifications
Storage Buffer	White to off-white solid
Storage Condition	-20°C
Target
Product Information	Cell-permeable, peptide aldehyde inhibitor of calpain I (Ki=190 nM), calpain II (Ki=150 nM), cathepsin L (Ki=0.5 nM) and other neutral cysteine proteases.1 Inhibits cell cycle progression at G1/S and metaphase/anaphase in CHO cells by inhibiting cyclin B degradation.2 Inhibits proteolytic degradation of IκBα and IκBβ in RAW macrophages induced with LPS.3 Blocks AIF-mediated necroptosis.4 Cell permeable.
Description	CAS Number: 110044-82-1 Chemical Name: Ac-Leu-Leu-Nle-CHO Molecular weight: 383.53 Formula: C20H37N3O4 Solubility: DMSO (10 mg/ml) Ethanol (5 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms)