Cinacalcet HCl

Overview
Catalog #	bs-82618c-10-mg
Product Name	Cinacalcet HCl
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Cinacalcet (364782-34-3) is a calcimimetic that allosterically activates the calcium-sensing receptor (CaSR; EC50 = 79.4 nM in HEK 293T cells expressing CaSR).1-3 It lowers plasma parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism.4 Cinacalcet has been used to treat parathyroid carcinoma.5
Description	CAS Number: 364782-34-3 Chemical Name: αR-Methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine hydrochloride Molecular weight: 393.88 Formula: C22H22F3N • HCl Solubility: DMSO (50 mg/ml) Water (5 mg/ml with warming) Physical Properties: White solid Purity: >98% by TLC NMR (Conforms)