Safinamide
| Overview | |
| Catalog # | bs-82611c-5-mg |
| Product Name | Safinamide |
| Specifications | |
| Storage Buffer | White or off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | A selective and reversible inhibitor of monoamine oxidase B (MAO-B, IC50=98 nM with greater than 100-fold selectivity over MAO-A.1 Displays anticonvulsant activity2 and protects against kainate-induced seizures and hippocampal neurodegeneration in rat models3. Reduces overactive glutamatergic signaling via use-dependent sodium channel blockade.4 A novel therapeutic for Parkinson’s disease with multiple modes of action.5 Effective as an add-on to dopamine agonist therapy in early Parkinson’s.6 |
| Description | CAS Number: 133865-89-1 Chemical Name: (S)-(+)-2-[[4-(3-Fluorobenzoxy)benzyl]amino]propanamide Molecular weight: 302.34 Formula: C17H19FN2O2 Solubility: DMSO (50 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMr (Conforms) |
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