Vildagliptin

Overview
Catalog #	bs-82604c-10-mg
Product Name	Vildagliptin
Specifications
Storage Buffer	Red solid
Storage Condition	-20°C
Target
Product Information	A potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that cleaves glucagon-like peptide 1 (GLP-1)1. Delaying the degradation of GLP-1 extends the action of insulin and suppressing the release of glucagon which results in reduction in elevated blood glucose levels (hyperglycemia)2. Clinically useful antidiabetic agent. Ameliorates cognitive deficits in streptozotocin-induced Alzheimers disease model3. Displays protective effects on β-cells by inhibition of ER stress in a mouse model4.
Description	CAS Number: 274901-16-5 Chemical Name: (S)-1-[N-(3-Hydroxy-1-adamantyl)glycyl]pyrrolidine-2-carbonitrile Molecular weight: 303.40 Formula: C17H25N3O2 Solubility: DMSO (45 mg/ml) DMF (20 mg/ml) Ethanol (20 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms)