Nicotinamide

Overview
Catalog #	bs-82594c-1-g
Product Name	Nicotinamide
Specifications
Storage Buffer	Red solid
Storage Condition	RT
Target
Product Information	Essential nutrient (amide form of Vitamin B3) that is incorporated into cofactors NADH/NAD+, important for ATP production and other key metabolic functions.1 Transiently inhibits SIRT1/SIRT3 through feedback inhibition (IC50 ~ 50 µM)2, but is quickly converted to NAD+ in cells3. Also inhibits certain kinases (e.g. ROCK and CK1), making it a regulator of hPSC pluripotency, survival, and differentiation.4 Inhibits differentiation and enhances functionality of hematopoietic stem/progenitor cells (HSPCs).5
Description	CAS Number: 98-92-0 Chemical Name: Pyridine-3-carboxylic acid amide Molecular weight: 122.13 Formula: C6H6N2O Solubility: DMSO (50 mg/ml); water (50 ml) Physical Properties: White solid Purity: >99% by HPLC, NMR (Conforms)