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Pimaricin (Natamycin)

Overview
Catalog # bs-82570c-50-mg
Product Name Pimaricin (Natamycin)
Specifications
Storage Buffer solid
Storage Condition -20°C
Target
Product Information Polyene macrolide topical antifungal agent. Specifically binds to ergosterol and inhibits fungal growth, not by forming pores in the plasma membrane (as is the case with other polyene macrolides such as amphotericin B)1 but by inhibition of amino acid and glucose transport2. Blocks vacuole fusion at the priming phase via binding to ergosterol3.
Description CAS Number: 7681-93-8

Chemical Name: Fermentation product from Streptomyces chattanoogensis

Molecular weight: 665.74

Formula: C33H47NO13

Solubility: DMSO (7 mg/ml) Ethanol - sparringly soluble, less then 1 mg/ml

Physical Properties: Cream colored solid

Purity: 95% by TLC, NMR (Conforms)