Chymostatin

Overview
Catalog #	bs-82567c-5-mg
Product Name	Chymostatin
Specifications
Storage Buffer	Off-white lyophilized solid (vial appear empty)
Storage Condition	-20°C
Target
Product Information	A potent, competitive, slow-binding inhibitor of α-, β-, γ-, δ-chymotrypsin, papain and cathepsins B/G (chymotryptase-like serine proteases)1, Ki=9.36 and 13.1 nM for chymotrypsin and chymase2. Cathepsin G Ki=0.15 μM.3 Consists of a mixture of type A (L-Leu), B (L-Val) and C (L-Ile) forms.1 Decreases plasma and tissue levels of angiotensin II without lowering mean blood pressure in a hypertensive rat model.4 Commonly used in lysis buffers to prevent degradation of proteins. Typical working concentration is 6-60 µg/ml.
Description	CAS Number: 9076-44-2 Chemical Name: [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-a-[2-amidohexahydro-4(S)-pyrimidyl]-(S)-glycyl-[A= Leu, B=Val, C=Ile]-phenylalaninal Molecular weight: 605.00 (average) Formula: C31H41N7O6 Solubility: DMSO (20 mg/ml) Physical Properties: White or off-white solid Purity: 96% by TLC NMR (Conforms)