Ivabradine HCl

Overview
Catalog #	bs-82562c-10-mg
Product Name	Ivabradine HCl
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Ivabradine (148849-67-6) is a clinically useful heart failure and chronic unstable angina medication.1 It lowers heart rate via inhibition of hyperpolarization-activated cyclic nucleotide-gated channels (HCN) expressed in the sinoatrial node (IC50’s: HCN1 = 2.05 µM, HCN2 = 2.29 µM, HCN3 = 2.51 µM, HCN4 = 2.15 µM).2
Description	CAS Number: 148849-67-6 Chemical Name: 3-[3-[[(7S)-3,4-Dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride Molecular weight: 505.05 Formula: C27H36N2O5·HCl Solubility: DMSO (20 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (Conforms)