Obatoclax

Overview
Catalog #	bs-82547c-5-mg
Product Name	Obatoclax
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	A novel Bcl-2 homology domain-3 (BH3) mimetic1. Inhibits primary acute myeloid leukemia (AML) progenitor cell proliferation (IC50=0.18 μM) and induces apoptosis in primary AML cells (IC50= 3.6 μM)2. Synergizes with other agents such as chloroquine3 and cytarabine4 in cytotoxicity against a variety of cancer cells.
Description	CAS Number: 803712-79-0 Chemical Name: 2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate Molecular weight: 413.50 Formula: C20H19N3O · CH3SO3H Solubility: DMSO (5 mg/ml) Physical Properties: Purple solid Purity: 98% by TLC