Monensin Na

Overview
Catalog #	bs-82546c-1-g
Product Name	Monensin Na
Specifications
Storage Buffer	White solid
Storage Condition	RT
Target
Product Information	Monovalent-selective ionophore antibiotic, typically employed as a Na+ ionophore.1 Interferes with vesicular transport through the Golgi aparatus2 and induces Golgi swelling3. Neutralizes intracellular compartments such as the trans Golgi apparatus cisternae, lysosomes, and certain endosomes4 (inducing EGFR endosomal arrest for example5). Induces the cleavage of full-length CREB3 in HEK293 cells.6
Description	CAS Number: 22373-78-0 Chemical Name: 2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-hydroxymethyl-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-β-methoxy-α,γ,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid, sodium salt Molecular weight: 692.86 Formula: C36H61O11·Na Solubility: DMSO (25 mg/ml with warming) Physical Properties: White solid Purity: 90-95% by TLC, NMR (Conforms)