AS-605240
| Overview | |
| Catalog # | bs-82524c-5-mg |
| Product Name | AS-605240 |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Potent and selective inhibitor of PI 3-kinase (PI 3-K ), IC50 = 8 nM displaying 30-fold selectivity over PI 3-K and PI 3-K and 7.5-fold selectivity over PI 3-K1. Suppresses joint inflammation in two distinct mouse models1. Ameliorates surgical brain injury2, colitis3, intimal hyperplasia-induced inflammatory processes4 and renal injury/fibrosis5 in rodent models. Orally active. |
| Description | CAS Number: 648450-29-7 Chemical Name: 5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione Molecular weight: 257.27 Formula: C12H7N3O2S Solubility: DMSO (1.5 mg/ml) Physical Properties: Red solid Purity: 98% by TLC NMR (Conforms) |
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