FAK inhibitor 14
| Overview | |
| Catalog # | bs-82519c-10-mg |
| Product Name | FAK inhibitor 14 |
| Specifications | |
| Storage Buffer | Tan solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. Prevents FAK autophosphorylation at Y397 (IC50 = 1 μM), promotes cell detachment and inhibits cell adhesion in vitro. Exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo. Induces regression of pancreatic tumors2 and glioblastoma3. Displays antiangiogenic activity4. |
| Description | CAS Number: 4506-66-5 Chemical Name: 1,2,4,5-Benzenetetramine tetrahydrochloride Molecular weight: 284.02 Formula: C6H10N4 · 4HCl Solubility: DMSO (20 mg/ml) water (15 mg/ml) Physical Properties: Grey solid Purity: 98% by TLC, NMR (Conforms) |
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