Bupropion HCl

Overview
Catalog #	bs-82501c-50-mg
Product Name	Bupropion HCl
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Clinically useful antidepressant that inhibits monoamine transporters DAT, NET, and SERT (Kis for dopamine uptake = 2.8, 1.4, 45 µM).1 Also acts as a noncompetitive antagonist at nicotinic acetylcholine receptors (AChRs).2 At higher concentrations (50 µM), stimulates pro-inflammatory cytokines and TLR2/TLR4 and JAK2/STAT3 in human peripheral blood mononuclear cells (PBMCs).3
Description	CAS Number: 31677-93-7 Chemical Name: 1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride Molecular weight: 276.2 Formula: C13H18ClNO·HCl Solubility: DMSO (40 mg/ml) Physical Properties: White solid Purity: >98% by HPLC, NMR (Conforms)