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Cyclothiazide

Overview
Catalog # bs-82497c-10-mg
Product Name Cyclothiazide
Specifications
Storage Buffer Yellow solid
Storage Condition RT
Target
Product Information Positive allosteric modulator of AMPA receptors acting at a site distinct from that of 2,3-benzodiazepines.1,2 Clinically useful diuretic and antihypertensive agent.3 Induces robust epileptiform activity, inducing seizures but without neuronal death.4,5 Can be used to produce a new animal model for epilepsy.5
Description CAS Number: 2259-96-3

Chemical Name: 6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide

Molecular weight: 389.88

Formula: C14H16ClN3O4S2

Solubility: DMSO (35 mg/ml) Ethanol (9 mg/ml)

Physical Properties: Off-white solid

Purity: 98% by TLC, NMR (Conforms)