Jervine

Overview
Catalog #	bs-82479c-5-mg
Product Name	Jervine
Specifications
Storage Buffer	Orange solid
Storage Condition	-20°C
Target
Product Information	Inhibitor of Hedgehog signaling (IC50 = 0.5-0.7 μM). Binds directly to Smoothened (Smo)1. Inhibits the response of target tissues to Sonic hedgehog signaling2. Induces COX-2 overexpression in human erythroleukemia cells3.
Description	CAS Number: 469-59-0 Chemical Name: (3β,23β)-17,23-Epoxy-3-hydroxyveratraman-11-one Molecular weight: 425.62 Formula: C27H39NO3 Solubility: DMSO (5 mg/ml) DMF (6 mg/ml) Ethanol (20 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)