Cilastatin Na

Overview
Catalog #	bs-82440c-10-mg
Product Name	Cilastatin Na
Specifications
Storage Buffer	Yellow solid
Storage Condition	-20°C
Target
Product Information	Dehydropeptidase-1 inhibitor. Inhibits the proteolytic conversion of leukotriene D4 to E4.1 Inhibits the mammalian β-lactamase renal dipeptidase (dehydropeptidase-1, DPEP1) and thus is used as an antibacterial adjunct to extend the half-life of β-lactam antibiotics.2 Cilastatin also inhibits bacterial metallo-β-lactamase and thereby may block resistance to the carbapenem family of antibiotics in certain bacteria.3 Suppresses invasion and metastasis of DPEP1-expressing tumor cells.4
Description	CAS Number: 81129-83-1 Chemical Name: (2Z)-7-[[(2R)-2-Amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]-carbonyl]amino]-2-heptenoic acid, sodium salt Molecular weight: 380.43 Formula: C16H25N2O5S Na Solubility: DMSO (3 mg/ml) Water (35 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms)